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NSF-sponsored Workshop: Cross-disciplinary study of Post-transcriptional and Post-translational Modifications

October 18 - October 20

Finding the commonalities of interests, approaches, and future directions

Virtual via zoom

In cell functions, post-transcriptional modifications (PRMs) of RNA molecules and post-translational modifications (PTMs) of proteins are important regulatory mechanisms. Yet significant gaps remain in the integrated understanding of PRMs and PTMs, and their effects on overall cellular signaling and metabolism. Fragmentated research efforts in different systems (e.g., microbe, plant, animal, and human) and using different approaches and standards, has prevented integrative analyses of different datasets and identification of common principles of PRMs and PTMs. This NSF-sponsored workshop aims to fill these critical gaps and advance research from descriptive and specific mechanistic focus towards integration, general theory, modeling and prediction, and global understanding. Moreover, this workshop will promote studying the functions and mechanisms of the key regulatory modifications, of their roles in cellular signaling and metabolism, as well as their impact on organisms. Collectively, this workshop will identify critical gaps in resources and understanding of PRMs and PTMs across disciplines, and importantly draft a path forward for community-wide collaborative research to advance these important areas that affect our understanding of human, plant, animal, and ecosystem biology.

This workshop is open to everyone at no cost. Here is a tentative schedule. Once you have registered (https://biotech.ufl.edu/event/nsf-sponsored-workshop-cross-disciplinary-study-of-post-transcriptional-and-post-translational-modifications/), you will receive the zoom link and can join us for this amazing two-and-a-half-day event.

///   REGISTER BELOW   ///

There is no cost for attending, but registration is required. Registration below.


October 18

October 19

October 20


Workshop Topics
U.S. EDT

9:00am – 9:30am   |   Welcome


    9:00am-9:30am

    9:30am – 10:30am    |    Opening Plenary Talks


      9:30am-10:30am
      MORNING BREAK
      10:30am-10:45am

      10:45am – 12:35pm   |    Methods for Discovering Modifications


      10:45am-12:35pm
      LUNCH BREAK
      12:35pm-1:30pm

      1:30pm – 3:00pm   |    Integration of Multi-‘omics Data


      1:30pm-3:00pm
      AFTERNOON BREAK
      3:00pm-3:20pm

      3:20pm – 5:00pm    |    Large Group Discussions

      3:20pm-5:00pm

      Contact
      Dr. Brian Gregory, Associate Professor of Biology, Graduate Chair, University of Pennsylvania 
      Dr. Sixue Chen, Professor of Biology, Faculty Director of Proteomics and Mass Spectrometry, ICBR, University of Florida

      3:00pm-3:20pm


      Workshop Topics
      U.S. EDT

      9:00am – 10:00am   |   Opening Plenary Talks 


      • RNA NAD+ Capping
        Dr. Xuemei Chen, University of California, Riverside
        9:00am-10:00am
        MORNING BREAK
        10:00am-10:30am

        10:30am – 12:20pm   |   Effects of Modifications on Phenotypes


        10:30am-12:20pm
        LUNCH BREAK
        12:20pm-1:20pm

        1:20pm – 3:10pm   |   Interplay Between RNA and Protein Modifications


        • Tracking post-transcriptional modifications in RNA networks to understand biological responses to environmentally-induced oxidative stress
          Dr. Lydia Contreras
        • A nanopore method for pseudoU detection and its application to interferon response in human cells
          Dr. Kristin Koutmou

        1:20pm-3:10pm
        AFTERNOON BREAK
        3:10pm-3:40pm

        3:40pm – 5:00pm   |   Large Group Discussions

        3:40pm-5:00pm

        Contact
        Dr. Brian Gregory, Associate Professor of Biology, Graduate Chair, University of Pennsylvania 
        Dr. Sixue Chen, Professor of Biology, Faculty Director of Proteomics and Mass Spectrometry, ICBR, University of Florida

        3:10pm-3:40pm


        Workshop Topics
        U.S. EDT

        9:00am – 10:30am   |   Big Ideas: Future


        9:00am-10:00am
        MORNING BREAK
        10:00am-10:30am

        11:00am – 12:30pm  |   Large Group Discussions

        11:00am-12:30pm

        12:30pm – 1:00pm  |  Conclusions by Dr. Brian Gregory

        11:00am-12:30pm

        Contact
        Dr. Brian Gregory, Associate Professor of Biology, Graduate Chair, University of Pennsylvania 
        Dr. Sixue Chen, Professor of Biology, Faculty Director of Proteomics and Mass Spectrometry, ICBR, University of Florida

        10:00am-10:30am


        Cross-disciplinary study of Post-transcriptional and Post-translational Modifications

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        Details

        Start:
        October 18
        End:
        October 20
        Event Categories:
        ,

        Organizer

        ICBR Proteomics & Mass Spectrometry
        Phone:
        (352) 273-8060
        Email:
        ICBR-Proteomics@ad.ufl.edu
        Website:
        https://biotech.ufl.edu/proteomics/