Bioinformatics

ICBR-Bioinformatics@ad.ufl.edu   ///  (352) 273-8049   ///    RRID: SCR_019120
Bioinformatics Consulting, Data Analytics, Single-Cell Analysis, Metagenomics & More

CORE OVERVIEW

The Bioinformatics core offers bioinformatics consulting and data analytics to help researchers analyze and understand the large data sets acquired from next generation sequencing and array-based technologies. We coordinate closely with other ICBR cores (Next-Gen Sequencing, Gene Expression, Cytometry, and Proteomics) on shared projects. 

We collaborate with researchers in designing experiments and analyzing complex datasets by applying various data-analytical and theoretical methods, mathematical modeling and computational techniques.  We develop and operate comprehensive pipelines enabling large-scale data processing, including NGS data analysis (e.g., RNA-Seq, DNA-Seq, methyl-Seq and ChIP-Seq) single-cell analysistranscriptome and genome annotation (project-based EST/genomic sequence assembly, annotation and gene prediction), variant detection, metagenomics (characterization of microbial communities) and microarray-based data analysis (statistical and functional data analysis from major microarray platforms).

Bioinformatics staff members have extensive experience in bioinformatics, genomics, transcriptomics and translational informatics in plant, animal and microbial systems. Our expertise includes big data analysis, statistical analysis, software development and high-performance computing. We strive to be scientific collaborators – rather than just service providers – using our expertise and skills to ensure the success of your projects.

Our services are offered at a standard hourly rate, and can be accessed on a fee-for-service basis or as long-term collaborations.

CORE NEWS

ICBR Closed for the Thanksgiving Holiday! ICBR Closed for the Thanksgiving Holiday!
ICBR Closed for the Thanksgiving Holiday!
Wishing you and yours a joyous Thanksgiving. Best wishes from your friends at UF | ICBR! ICBR will be closed all day Thursday and Friday (November 27th and 28th); returning on Monday (December 1st). We here at ICBR are thankful for you, and hope you enjoy the holiday! And a special thank you the near thousand users that came through our doors this year, including 300+ PIs from over a hundred UF departments! We look forward to working with you 2025!     Normal business hours will resume...
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ICBR Closed for the Thanksgiving Holiday!
Covid-19 Vaccines Enhance the Effectiveness of Immune Checkpoint Inhibitors in Fighting Cancer Covid-19 Vaccines Enhance the Effectiveness of Immune Checkpoint Inhibitors in Fighting Cancer
Covid-19 Vaccines Enhance the Effectiveness of Immune Checkpoint Inhibitors in Fighting Cancer
Covid-19 Vaccines Enhance the Effectiveness of Immune Checkpoint Inhibitors in Fighting Cancer Steven J. Madore, PhD (ICBR Associate Director for Science, UFHCI Associate Director for Shared Resources) Tumor cells fend off the attacks of immune system T-cells by expressing proteins like PD-L1 on their cell surface.  The PD-L1 on the surface of the tumor cell binds to a T-cell surface receptor protein called PD-1 and silences the killing action of the T-cells. Blocking the binding of PD-L1 to PD...
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Covid-19 Vaccines Enhance the Effectiveness of Immune Checkpoint Inhibitors in Fighting Cancer
ICBR Closed Tuesday (11/11) for Veterans Day ICBR Closed Tuesday (11/11) for Veterans Day
ICBR Closed Tuesday (11/11) for Veterans Day
ICBR Closed Tuesday for Veterans Day ICBR will be closed Tuesday, November 11th in observation of Veterans Day   We will not be accepting packages or samples on Tuesday. Our normal business hours will resume on Wednesday (11/12). Enjoy the the long weekend!   Please refer to our staff directory for additional details. ...
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ICBR Closed Tuesday (11/11) for Veterans Day
ICBR Closed for Homecoming, Friday, October 17th ICBR Closed for Homecoming, Friday, October 17th
ICBR Closed for Homecoming, Friday, October 17th
UF | ICBR will be closed on Friday, October 17th in observance of UF Homecoming. Please enjoy the long weekend! Normal business hours will resume on Monday, October 20th. ...
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ICBR Closed for Homecoming, Friday, October 17th
ICBR Closed Monday for Labor Day ICBR Closed Monday for Labor Day
ICBR Closed Monday for Labor Day
ICBR Closed Monday for Labor Day ICBR will be closed this Monday (9/1) in observation of Labor Day   We will not be accepting packages or samples on Monday. Our normal business hours will resume on Tuesday (9/2). Enjoy the the long weekend!   Please refer to our staff directory for additional details. ...
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ICBR Closed Monday for Labor Day
UF plant biologist Anna-Lisa Paul receives SURA’s Distinguished Scientist Award UF plant biologist Anna-Lisa Paul receives SURA’s Distinguished Scientist Award
UF plant biologist Anna-Lisa Paul receives SURA’s Distinguished Scientist Award
UF plant biologist Anna-Lisa Paul receives SURA’s Distinguished Scientist Award by Joe Kays University of Florida plant molecular biologist Anna-Lisa Paul has been named a recipient of the Southeastern Universities Research Association’s (SURA) 2025 Distinguished Scientist Award, recognizing her groundbreaking contributions to space biology and her leadership in advancing scientific exploration beyond Earth. Paul is the director of UF’s Interdisciplinary Center for Biotechnology Research (ICBR),...
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UF plant biologist Anna-Lisa Paul receives SURA’s Distinguished Scientist Award
Environmental DNA – It’s All Up in the Air Environmental DNA – It’s All Up in the Air
Environmental DNA – It’s All Up in the Air
Environmental DNA – It’s All Up in the Air Steven J. Madore, PhD (ICBR Associate Director for Science) (Note: this article has been summarized from UF News “Environmental DNA floating in the air tracks wildlife, viruses — even drugs” June 3, 2025 by Eric Hamilton) Scientists can now use the power of genetic information to identify biodiversity by sampling environmental DNA or eDNA. “The level of information that’s available in environmental DNA is such that we’re only starting to consider what t...
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Environmental DNA – It’s All Up in the Air
UF Investigators Identify Mechanism of Drug Resistance in Non-Small Cell Lung Cancer UF Investigators Identify Mechanism of Drug Resistance in Non-Small Cell Lung Cancer
UF Investigators Identify Mechanism of Drug Resistance in Non-Small Cell Lung Cancer
UF Investigators Identify Mechanism of Drug Resistance in Non-Small Cell Lung Cancer Steven J Madore, PhD (ICBR Associate Director for Science) Summarized from J. Clin. Inv. 2025;135(6); e185149 Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related deaths worldwide. Despite a combination of surgery and chemotherapy, survival rate remains low due to cancer cell metastasis and drug resistance.  Mutations in the oncogene KRAS are frequently found in human cancers, including up to ...
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UF Investigators Identify Mechanism of Drug Resistance in Non-Small Cell Lung Cancer