LTQ Orbitrap XL System

UF | ICBR Proteomics & Mass Spectrometry

Combining fast, sensitive linear ion trap MSn with high-resolution, accurate-mass (HR/AM) Orbitrap™ technology, the research-proven Thermo Scientific LTQ Orbitrap XL system provides economical access to the power of hybrid ion trap-Orbitrap analysis. With outstanding mass accuracy, resolving power, high sensitivity and MSn capability, the LTQ Orbitrap XL™ instrument is the instrument of choice for confident, reliable detection, identification, and characterization. The standard higher-energy collisional dissociation (HCD) collision cell provides exceptional flexibility in fragmentation for advanced proteomics and small-molecule research. The optional electron transfer dissociation (ETD) generates complementary information for highly sensitive PTM analyses and de novo sequencing.


Routine FT mass accuracy

Resolving power > 100,000

Wide dynamic range

Parallel MS and MSn analysis

Multiple dissociation techniques: CID, PQD and HCD

ETD upgradeable


Mass Range

m/z 50-2,000, m/z 200-4,000


60,000 at m/z 400 at a scan (FWHM) rate of 1 Hz

Minimum resolution 7,500

Maximum resolution > 100,000 at m/z 400

Mass Accuracy

< 3 ppm RMS with external calibration

< 1 ppm RMS using internal calibration


Sub-femtomol range for peptides

Dynamic Range

> 4,000 within a single scan guaranteeing specified mass accuracy

MS Scan Power

MSn, for n = 1 through 10

Resources for Optimal Performance of your
LTQ Orbitrap XL Mass Spectrometer

We know you, or someone you know, worked very hard to get your Orbitrap-based mass spectrometer in your lab and even harder preparing your precious samples. We are working just as hard to make sure that you have the latest information and all the additional resources you need to produce the highest quality data to ensure you get the results that you need.

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